STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_0739TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: dsy:DSY2429 hypothetical protein; Belongs to the thioredoxin family. (104 aa)    
Predicted Functional Partners:
Cphy_1503
Thioredoxin-disulfide reductase; PFAM: glucose-inhibited division protein A; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cth:Cthe_1945 thioredoxin-disulfide reductase.
 
 0.910
Cphy_0254
TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; HI0933 family protein; KEGG: tte:TTE2220 thioredoxin reductase.
 
 
 0.906
Cphy_2155
PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: cbe:Cbei_2111 protein tyrosine phosphatase.
  
 
 0.728
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
 
 
 0.713
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 
 0.590
Cphy_0321
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ctc:CTC02435 sarcosine oxidase alpha subunit.
  
 
 0.561
Cphy_3393
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tde:TDE0135 pyridine nucleotide-disulphide oxidoreductase family protein.
  
 
 0.561
Cphy_3470
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA family protein; Rhodanese domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: drm:Dred_2967 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Belongs to the sulfur carrier protein TusA family.
  
  
 0.550
Cphy_1514
PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tte:TTE2131 NADH:flavin oxidoreductase, Old Yellow enzyme family.
  
 
 0.537
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
  
 0.532
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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