| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cphy_1122 | Cphy_1124 | Cphy_1122 | Cphy_1124 | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: amt:Amet_4190 transcriptional regulator, RpiR family. | PFAM: conserved hypothetical protein; KEGG: cac:CAC0185 uncharacterized membrane protein, YBBC B.subtilis ortholog. | 0.675 |
| Cphy_1122 | Cphy_1125 | Cphy_1122 | Cphy_1125 | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: amt:Amet_4190 transcriptional regulator, RpiR family. | PFAM: glycoside hydrolase family 3 domain protein; KEGG: tte:TTE0215 Beta-glucosidase-related glycosidases. | 0.492 |
| Cphy_1122 | Cphy_1126 | Cphy_1122 | Cphy_1126 | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: amt:Amet_4190 transcriptional regulator, RpiR family. | PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: cac:CAC0183 transcriptional regulators of NagC/XylR (ROK) family, sugar kinase. | 0.690 |
| Cphy_1122 | Cphy_1768 | Cphy_1122 | Cphy_1768 | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: amt:Amet_4190 transcriptional regulator, RpiR family. | KEGG: cbe:Cbei_0751 PTS system, glucose subfamily, IIA subunit; TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, glucose-like IIB subunint; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC. | 0.857 |
| Cphy_1122 | Cphy_1799 | Cphy_1122 | Cphy_1799 | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: amt:Amet_4190 transcriptional regulator, RpiR family. | PFAM: glycoside hydrolase family 18; Carbohydrate-binding family V/XII; SMART: chitinase II; KEGG: sco:SCO5003 chinitase A precursor; Belongs to the glycosyl hydrolase 18 family. | 0.420 |
| Cphy_1122 | Cphy_2838 | Cphy_1122 | Cphy_2838 | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: amt:Amet_4190 transcriptional regulator, RpiR family. | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: pth:PTH_0142 hypothetical protein. | 0.453 |
| Cphy_1122 | anmK | Cphy_1122 | Cphy_1123 | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: amt:Amet_4190 transcriptional regulator, RpiR family. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.841 |
| Cphy_1122 | birA | Cphy_1122 | Cphy_2779 | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: amt:Amet_4190 transcriptional regulator, RpiR family. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.430 |
| Cphy_1122 | murQ | Cphy_1122 | Cphy_1121 | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: amt:Amet_4190 transcriptional regulator, RpiR family. | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | 0.712 |
| Cphy_1124 | Cphy_1122 | Cphy_1124 | Cphy_1122 | PFAM: conserved hypothetical protein; KEGG: cac:CAC0185 uncharacterized membrane protein, YBBC B.subtilis ortholog. | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: amt:Amet_4190 transcriptional regulator, RpiR family. | 0.675 |
| Cphy_1124 | Cphy_1125 | Cphy_1124 | Cphy_1125 | PFAM: conserved hypothetical protein; KEGG: cac:CAC0185 uncharacterized membrane protein, YBBC B.subtilis ortholog. | PFAM: glycoside hydrolase family 3 domain protein; KEGG: tte:TTE0215 Beta-glucosidase-related glycosidases. | 0.869 |
| Cphy_1124 | Cphy_1126 | Cphy_1124 | Cphy_1126 | PFAM: conserved hypothetical protein; KEGG: cac:CAC0185 uncharacterized membrane protein, YBBC B.subtilis ortholog. | PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: cac:CAC0183 transcriptional regulators of NagC/XylR (ROK) family, sugar kinase. | 0.889 |
| Cphy_1124 | anmK | Cphy_1124 | Cphy_1123 | PFAM: conserved hypothetical protein; KEGG: cac:CAC0185 uncharacterized membrane protein, YBBC B.subtilis ortholog. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.653 |
| Cphy_1124 | murQ | Cphy_1124 | Cphy_1121 | PFAM: conserved hypothetical protein; KEGG: cac:CAC0185 uncharacterized membrane protein, YBBC B.subtilis ortholog. | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | 0.615 |
| Cphy_1125 | Cphy_1122 | Cphy_1125 | Cphy_1122 | PFAM: glycoside hydrolase family 3 domain protein; KEGG: tte:TTE0215 Beta-glucosidase-related glycosidases. | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: amt:Amet_4190 transcriptional regulator, RpiR family. | 0.492 |
| Cphy_1125 | Cphy_1124 | Cphy_1125 | Cphy_1124 | PFAM: glycoside hydrolase family 3 domain protein; KEGG: tte:TTE0215 Beta-glucosidase-related glycosidases. | PFAM: conserved hypothetical protein; KEGG: cac:CAC0185 uncharacterized membrane protein, YBBC B.subtilis ortholog. | 0.869 |
| Cphy_1125 | Cphy_1126 | Cphy_1125 | Cphy_1126 | PFAM: glycoside hydrolase family 3 domain protein; KEGG: tte:TTE0215 Beta-glucosidase-related glycosidases. | PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: cac:CAC0183 transcriptional regulators of NagC/XylR (ROK) family, sugar kinase. | 0.807 |
| Cphy_1125 | Cphy_1768 | Cphy_1125 | Cphy_1768 | PFAM: glycoside hydrolase family 3 domain protein; KEGG: tte:TTE0215 Beta-glucosidase-related glycosidases. | KEGG: cbe:Cbei_0751 PTS system, glucose subfamily, IIA subunit; TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, glucose-like IIB subunint; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC. | 0.431 |
| Cphy_1125 | anmK | Cphy_1125 | Cphy_1123 | PFAM: glycoside hydrolase family 3 domain protein; KEGG: tte:TTE0215 Beta-glucosidase-related glycosidases. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.717 |
| Cphy_1125 | murQ | Cphy_1125 | Cphy_1121 | PFAM: glycoside hydrolase family 3 domain protein; KEGG: tte:TTE0215 Beta-glucosidase-related glycosidases. | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | 0.477 |