STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_1137PFAM: NUDIX hydrolase; Zinc ribbon NADH pyrophosphatase; KEGG: lpl:lp_3123 pyrophosphatase (putative). (286 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
 
 0.925
Cphy_3836
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
    
 0.923
cobB
Silent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
  
 
 0.919
Cphy_1981
5'-nucleotidase; PFAM: 5-nucleotidase; KEGG: har:HEAR0649 putative 5'-nucleotidase.
  
  
  0.912
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.908
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.904
Cphy_1253
PFAM: metallophosphoesterase; KEGG: bcl:ABC0966 nucleotidase; Belongs to the 5'-nucleotidase family.
    
  0.903
Cphy_2453
PFAM: CinA domain protein; KEGG: tte:TTE1375 predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA.
     
 0.903
Cphy_3434
PFAM: metallophosphoesterase; KEGG: sak:SAK_1901 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic precursor protein.
    
  0.903
Cphy_1452
PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: bcy:Bcer98_2341 5'-nucleotidase domain protein; Belongs to the 5'-nucleotidase family.
    
  0.517
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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