STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_1142KEGG: dsy:DSY1749 hypothetical protein. (186 aa)    
Predicted Functional Partners:
Cphy_1143
KEGG: amt:Amet_2169 hypothetical protein.
       0.676
Cphy_1144
PFAM: band 7 protein; KEGG: amt:Amet_2170 band 7 protein.
       0.655
Cphy_0208
PFAM: heat shock protein DnaJ domain protein; KEGG: cbf:CLI_0254 molecular chaperone, DnaJ family.
  
 
 0.457
Cphy_2171
PFAM: heat shock protein DnaJ domain protein.
  
 
 0.457
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.457
Cphy_1141
KEGG: amt:Amet_3459 hypothetical protein.
       0.450
Cphy_0628
KEGG: csc:Csac_1211 glutamine synthetase, type I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp.
  
 
 0.440
Cphy_1145
PFAM: carbohydrate kinase FGGY; KEGG: cbe:Cbei_4452 carbohydrate kinase, FGGY.
       0.417
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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