Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Cphy_1188Peptidase S41; PFAM: TPR repeat-containing protein; peptidase S41; RDD domain containing protein; Tetratricopeptide TPR_3; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cth:Cthe_2680 peptidase S41. (897 aa)    
Predicted Functional Partners:
Cphy_0265
KEGG: sbl:Sbal_2840 hypothetical protein.
  
 0.976
Cphy_3369
PFAM: heat shock protein Hsp90; KEGG: cth:Cthe_0550 heat shock protein HSP90.
  
 0.918
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.891
Cphy_0533
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cth:Cthe_2680 peptidase S41.
 
 
 0.870
Cphy_0459
Hypothetical protein.
  
 
 0.850
Cphy_0208
PFAM: heat shock protein DnaJ domain protein; KEGG: cbf:CLI_0254 molecular chaperone, DnaJ family.
   
 0.819
Cphy_2171
PFAM: heat shock protein DnaJ domain protein.
   
 0.819
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 0.819
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.795
Cphy_2029
Hypothetical protein; KEGG: amt:Amet_3803 copper amine oxidase domain protein.
  
 
 0.794
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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