Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_1336PFAM: peptidase U32; KEGG: ctc:CTC02275 protease. (817 aa)    
Predicted Functional Partners:
Cphy_2292
PFAM: O-methyltransferase family 3; KEGG: cbh:CLC_2427 O-methyltransferase family protein.
 
  
 0.708
Cphy_1080
PFAM: peptidase U32; KEGG: eba:ebA5191 conserved hypothetical protein, predicted peptidase U32 family.
  
     0.672
Cphy_1335
Protein of unknown function DUF710; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
     
 0.633
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
       0.536
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
       0.527
Cphy_1337
PFAM: cell cycle protein; penicillin-binding protein transpeptidase; KEGG: ckl:CKL_3568 predicted peptidoglycan synthetase.
       0.522
Cphy_1338
PFAM: NUDIX hydrolase; KEGG: cdf:CD3398 putative DNA repair protein (nucleotide pyrophosphatase); Belongs to the Nudix hydrolase family.
       0.500
Cphy_1307
PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: cth:Cthe_3110 UBA/ThiF-type NAD/FAD binding fold.
  
     0.479
Cphy_3486
PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: cth:Cthe_3110 UBA/ThiF-type NAD/FAD binding fold.
  
     0.412
Cphy_1733
KEGG: cth:Cthe_3021 Ech hydrogenase, subunit EchD, putative.
   
   0.406
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.