| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cphy_1496 | Cphy_1497 | Cphy_1496 | Cphy_1497 | Dihydropyrimidinase; KEGG: efa:EF2580 D-hydantoinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase. | TIGRFAM: selenium-dependent molybdenum hydroxylase 1; PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; ferredoxin; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: cbe:Cbei_1982 aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding. | 0.890 |
| Cphy_1496 | Cphy_1498 | Cphy_1496 | Cphy_1498 | Dihydropyrimidinase; KEGG: efa:EF2580 D-hydantoinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase. | PFAM: Xanthine/uracil/vitamin C permease; KEGG: efa:EF2573 xanthine/uracil permease family protein. | 0.786 |
| Cphy_1496 | Cphy_3350 | Cphy_1496 | Cphy_3350 | Dihydropyrimidinase; KEGG: efa:EF2580 D-hydantoinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase. | KEGG: cac:CAC1655 bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain); TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein. | 0.530 |
| Cphy_1496 | carB | Cphy_1496 | Cphy_0541 | Dihydropyrimidinase; KEGG: efa:EF2580 D-hydantoinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: cth:Cthe_0949 carbamoyl-phosphate synthase, large subunit. | 0.876 |
| Cphy_1496 | pyrB | Cphy_1496 | Cphy_2750 | Dihydropyrimidinase; KEGG: efa:EF2580 D-hydantoinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase. | KEGG: cbf:CLI_3380 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.968 |
| Cphy_1496 | pyrD | Cphy_1496 | Cphy_2286 | Dihydropyrimidinase; KEGG: efa:EF2580 D-hydantoinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase. | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.903 |
| Cphy_1496 | pyrE | Cphy_1496 | Cphy_2285 | Dihydropyrimidinase; KEGG: efa:EF2580 D-hydantoinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.851 |
| Cphy_1496 | pyrF | Cphy_1496 | Cphy_0882 | Dihydropyrimidinase; KEGG: efa:EF2580 D-hydantoinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase. | TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: amt:Amet_4212 orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.851 |
| Cphy_1497 | Cphy_1496 | Cphy_1497 | Cphy_1496 | TIGRFAM: selenium-dependent molybdenum hydroxylase 1; PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; ferredoxin; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: cbe:Cbei_1982 aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding. | Dihydropyrimidinase; KEGG: efa:EF2580 D-hydantoinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase. | 0.890 |
| Cphy_1497 | Cphy_1498 | Cphy_1497 | Cphy_1498 | TIGRFAM: selenium-dependent molybdenum hydroxylase 1; PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; ferredoxin; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: cbe:Cbei_1982 aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding. | PFAM: Xanthine/uracil/vitamin C permease; KEGG: efa:EF2573 xanthine/uracil permease family protein. | 0.812 |
| Cphy_1498 | Cphy_1496 | Cphy_1498 | Cphy_1496 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: efa:EF2573 xanthine/uracil permease family protein. | Dihydropyrimidinase; KEGG: efa:EF2580 D-hydantoinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase. | 0.786 |
| Cphy_1498 | Cphy_1497 | Cphy_1498 | Cphy_1497 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: efa:EF2573 xanthine/uracil permease family protein. | TIGRFAM: selenium-dependent molybdenum hydroxylase 1; PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; ferredoxin; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: cbe:Cbei_1982 aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding. | 0.812 |
| Cphy_1498 | Cphy_3346 | Cphy_1498 | Cphy_3346 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: efa:EF2573 xanthine/uracil permease family protein. | PFAM: Xanthine/uracil/vitamin C permease; KEGG: dsy:DSY2917 hypothetical protein. | 0.717 |
| Cphy_1498 | Cphy_3350 | Cphy_1498 | Cphy_3350 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: efa:EF2573 xanthine/uracil permease family protein. | KEGG: cac:CAC1655 bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain); TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein. | 0.730 |
| Cphy_1498 | carB | Cphy_1498 | Cphy_0541 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: efa:EF2573 xanthine/uracil permease family protein. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: cth:Cthe_0949 carbamoyl-phosphate synthase, large subunit. | 0.755 |
| Cphy_1498 | pyrB | Cphy_1498 | Cphy_2750 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: efa:EF2573 xanthine/uracil permease family protein. | KEGG: cbf:CLI_3380 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.849 |
| Cphy_1498 | pyrD | Cphy_1498 | Cphy_2286 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: efa:EF2573 xanthine/uracil permease family protein. | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.684 |
| Cphy_1498 | pyrE | Cphy_1498 | Cphy_2285 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: efa:EF2573 xanthine/uracil permease family protein. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.730 |
| Cphy_1498 | pyrF | Cphy_1498 | Cphy_0882 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: efa:EF2573 xanthine/uracil permease family protein. | TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: amt:Amet_4212 orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.774 |
| Cphy_1498 | xpt | Cphy_1498 | Cphy_3381 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: efa:EF2573 xanthine/uracil permease family protein. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.928 |