STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_1534PFAM: Endonuclease/exonuclease/phosphatase; KEGG: lca:LSEI_2779 metal-dependent hydrolase. (367 aa)    
Predicted Functional Partners:
Cphy_1768
KEGG: cbe:Cbei_0751 PTS system, glucose subfamily, IIA subunit; TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, glucose-like IIB subunint; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC.
     
 0.571
Cphy_2948
KEGG: ckl:CKL_3246 hypothetical protein.
   
  
 0.525
Cphy_1010
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mac:MA0999 hypothetical protein.
  
    0.435
Cphy_0119
PFAM: binding-protein-dependent transport systems inner membrane component; Substrate-binding region of ABC-type glycine betaine transport system; KEGG: cbe:Cbei_2870 substrate-binding region of ABC-type glycine betaine transport system.
   
    0.427
Cphy_0097
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: lsl:LSL_1338 DNA-binding protein.
  
     0.415
mprF
Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
  
  
 0.414
secF
Protein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
       0.405
Cphy_0053
KEGG: cth:Cthe_2712 hypothetical protein.
  
    0.401
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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