Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Cphy_1551TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: det:DET0533 HAD-superfamily hydrolase, subfamily IA. (224 aa)    
Predicted Functional Partners:
Cphy_1550
KEGG: llm:llmg_1837 hypothetical protein.
       0.723
Cphy_3360
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: tde:TDE1878 hydrolase, haloacid dehalogenase-like family.
  
     0.660
Cphy_2162
PFAM: GCN5-related N-acetyltransferase; KEGG: lic:LIC12825 hypothetical protein.
 
    0.631
Cphy_0658
KEGG: pmy:Pmen_4204 hypothetical protein.
 
     0.568
Cphy_1549
Hypothetical protein; KEGG: efa:EF1234 ABC transporter, substrate-binding protein, putative.
       0.554
Cphy_1796
PFAM: beta-lactamase domain protein; KEGG: cbe:Cbei_3495 beta-lactamase domain protein.
 
    0.474
Cphy_2123
SMART: transglutaminase domain protein; KEGG: ssa:SSA_0384 hypothetical protein.
  
     0.471
Cphy_1306
KEGG: cbf:CLI_0627 hypothetical protein.
  
  
  0.452
lon
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
 
  0.417
Cphy_1089
PFAM: extracellular solute-binding protein family 1; KEGG: dsy:DSY1083 hypothetical protein.
  
     0.410
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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