Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_1562KEGG: cbf:CLI_0519 hypothetical protein. (331 aa)    
Predicted Functional Partners:
Cphy_1564
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cbo:CBO0432 pyridine nucleotide-disulphide oxidoreductase.
 
     0.888
hypA
Hydrogenase expression/synthesis HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
     0.836
Cphy_1563
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: cbh:CLC_0506 hydrogenase accessory protein HypB.
 
     0.749
Cphy_1561
PFAM: regulatory protein GntR HTH; KEGG: chy:CHY_0434 transcriptional regulator, GntR family.
 
     0.668
Cphy_1808
PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: cac:CAC0669 hypothetical protein.
  
     0.482
Cphy_0077
PFAM: ABC-2 type transporter; KEGG: spa:M6_Spy0585 SagH.
  
     0.443
Cphy_1696
Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; Penicillinase repressor; KEGG: amt:Amet_1479 transcriptional regulator, TrmB.
  
     0.412
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.