STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase expression/synthesis HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (113 aa)    
Predicted Functional Partners:
Cphy_1564
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cbo:CBO0432 pyridine nucleotide-disulphide oxidoreductase.
 
   
 0.956
Cphy_1563
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: cbh:CLC_0506 hydrogenase accessory protein HypB.
 
 
 0.953
Cphy_1737
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: cth:Cthe_3017 hydrogenase accessory protein HypB.
 
 
 0.899
Cphy_1562
KEGG: cbf:CLI_0519 hypothetical protein.
 
     0.836
Cphy_3558
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cno:NT01CX_1854 pyruvate:ferredoxin (flavodoxin) oxidoreductase.
  
  
 0.711
Cphy_0603
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cdf:CD2682 pyruvate-flavodoxin oxidoreductase.
     
 0.680
Cphy_1740
PFAM: hydrogenase formation HypD protein; KEGG: cth:Cthe_3014 hydrogenase formation HypD protein.
 
  
 0.668
hypA-2
Hydrogenase expression/synthesis HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
     0.656
Cphy_1741
TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: cth:Cthe_3013 hydrogenase expression/formation protein HypE.
 
  
 0.629
Cphy_1738
TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: SUA5/yciO/yrdC domain; zinc finger HypF domain protein; KEGG: cth:Cthe_3016 (NiFe) hydrogenase maturation protein HypF.
 
   
 0.602
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.