Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Cphy_1621Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: ckl:CKL_3004 predicted sensory transduction histidine kinase. (436 aa)    
Predicted Functional Partners:
Cphy_1620
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ckl:CKL_3005 predicted transcriptional regulator.
 
 
 0.974
Cphy_2838
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: pth:PTH_0142 hypothetical protein.
 
 
0.859
Cphy_1679
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: amt:Amet_1917 two component transcriptional regulator, winged helix family.
 
 
 0.803
Cphy_1861
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: amt:Amet_1917 two component transcriptional regulator, winged helix family.
 
 
 0.798
Cphy_0963
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cbe:Cbei_2249 two component transcriptional regulator, winged helix family.
 
 
 0.795
Cphy_3518
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cbf:CLI_0437 DNA-binding response regulator.
 
 
 0.771
Cphy_0015
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: amt:Amet_1506 two component transcriptional regulator, winged helix family.
 
 
 0.768
Cphy_2121
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cth:Cthe_1847 two component transcriptional regulator, winged helix family.
 
 
 0.768
Cphy_1676
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cac:CAC1506 response regulator (CheY-like receiver domain and a HTH).
 
 
 0.766
Cphy_0358
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cpf:CPF_1192 DNA-binding response regulator.
 
 
 0.752
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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