Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Cphy_1654TIGRFAM: RNA methyltransferase, TrmA family; PFAM: protein of unknown function Met10; conserved hypothetical protein; (Uracil-5)-methyltransferase; KEGG: cth:Cthe_1751 RNA methyltransferase, TrmA family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (554 aa)    
Predicted Functional Partners:
Cphy_1655
KEGG: ckl:CKL_0533 hypothetical protein.
       0.578
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
 
  
 0.486
Cphy_2838
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: pth:PTH_0142 hypothetical protein.
  
  
 0.442
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.435
hisI
TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: cth:Cthe_2889 phosphoribosyl-AMP cyclohydrolase; In the C-terminal section; belongs to the PRA-PH family.
  
    0.426
pheT
KEGG: cth:Cthe_0215 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
 
  
 0.417
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
 
   
 0.403
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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