STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_1656PFAM: DSBA oxidoreductase; KEGG: efa:EF1088 hypothetical protein. (231 aa)    
Predicted Functional Partners:
Cphy_1114
PFAM: NADPH-dependent FMN reductase; KEGG: dsy:DSY1214 hypothetical protein.
 
    0.577
Cphy_0206
PFAM: arsenate reductase and related; KEGG: ctc:CTC01181 arsenate reductase; Belongs to the ArsC family.
   
 
 0.489
Cphy_0726
PFAM: arsenate reductase and related; KEGG: cno:NT01CX_2298 arsenate reductase-like protein; Belongs to the ArsC family.
    
 
 0.479
Cphy_1655
KEGG: ckl:CKL_0533 hypothetical protein.
       0.461
Cphy_0995
KEGG: dsy:DSY1051 hypothetical protein.
  
    0.446
Cphy_1657
KEGG: bth:BT_2376 hypothetical protein.
       0.405
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.404
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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