Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_1690KEGG: cth:Cthe_1401 hypothetical protein. (116 aa)    
Predicted Functional Partners:
Cphy_1689
PFAM: sodium/hydrogen exchanger; KEGG: cbh:CLC_2648 transporter, monovalent cation:proton antiporter-2 (CPA2) family.
 
   
 0.920
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
    
 
 0.832
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.616
Cphy_0628
KEGG: csc:Csac_1211 glutamine synthetase, type I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp.
  
 
 0.555
Cphy_1707
KEGG: ani:AN4010.2 hypothetical protein.
   
 
 0.547
Cphy_3350
KEGG: cac:CAC1655 bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain); TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein.
     
 0.508
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.459
Cphy_0804
KEGG: mac:MA3471 hypothetical protein.
 
     0.455
Cphy_3111
PFAM: sodium/hydrogen exchanger; KEGG: cdf:CD0657 putative Na(+)/H(+) antiporter.
 
    0.446
Cphy_3620
PFAM: sodium/hydrogen exchanger; KEGG: cbh:CLC_1237 transporter, monovalent cation:proton antiporter-2 (CPA2) family.
 
   
 0.440
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
Server load: low (18%) [HD]