Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Cphy_1731PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: cth:Cthe_3023 respiratory-chain NADH dehydrogenase, subunit 1. (286 aa)    
Predicted Functional Partners:
Cphy_1732
PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: cth:Cthe_3022 NADH ubiquinone oxidoreductase, 20 kDa subunit.
 
 
 0.996
Cphy_1730
NADH dehydrogenase (quinone); PFAM: NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; NADH/Ubiquinone/plastoquinone (complex I); KEGG: cth:Cthe_3024 NADH dehydrogenase (quinone).
   
 0.988
Cphy_1734
PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; KEGG: cth:Cthe_3020 NADH dehydrogenase (ubiquinone); Belongs to the complex I 49 kDa subunit family.
 
 
 0.988
Cphy_1735
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cth:Cthe_3019 4Fe-4S ferredoxin, iron-sulfur binding.
 
 
 0.977
Cphy_1733
KEGG: cth:Cthe_3021 Ech hydrogenase, subunit EchD, putative.
 
 
 0.940
Cphy_3558
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cno:NT01CX_1854 pyruvate:ferredoxin (flavodoxin) oxidoreductase.
  
 
 0.889
Cphy_3754
4Fe-4S ferredoxin iron-sulfur binding domain protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
  
 
 0.835
hypA-2
Hydrogenase expression/synthesis HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
    0.639
Cphy_1739
TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: cth:Cthe_3015 hydrogenase assembly chaperone HypC/HupF.
 
     0.593
Cphy_1738
TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: SUA5/yciO/yrdC domain; zinc finger HypF domain protein; KEGG: cth:Cthe_3016 (NiFe) hydrogenase maturation protein HypF.
     
 0.483
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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