| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cphy_1369 | Cphy_1371 | Cphy_1369 | Cphy_1371 | TIGRFAM: siroheme synthase; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | 0.999 |
| Cphy_1369 | Cphy_1375 | Cphy_1369 | Cphy_1375 | TIGRFAM: siroheme synthase; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: ckl:CKL_0727 CbiL; Belongs to the precorrin methyltransferase family. | 0.958 |
| Cphy_1369 | Cphy_1379 | Cphy_1369 | Cphy_1379 | TIGRFAM: siroheme synthase; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | TIGRFAM: precorrin-6x reductase; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Precorrin-6x reductase CbiJ/CobK; KEGG: ctc:CTC00734 precorrin-6B methylase/decarboxylase cbiT/cbiE. | 0.836 |
| Cphy_1369 | Cphy_1387 | Cphy_1369 | Cphy_1387 | TIGRFAM: siroheme synthase; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | Anaerobic cobalt chelatase; PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; anaerobic cobalt chelatase; KEGG: cno:NT01CX_0573 anaerobic cobalt chelatase. | 0.913 |
| Cphy_1369 | Cphy_1779 | Cphy_1369 | Cphy_1779 | TIGRFAM: siroheme synthase; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | Anaerobic cobalt chelatase; PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; anaerobic cobalt chelatase; KEGG: tde:TDE2656 cobalt chelatase. | 0.908 |
| Cphy_1369 | Cphy_1785 | Cphy_1369 | Cphy_1785 | TIGRFAM: siroheme synthase; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | TIGRFAM: siroheme synthase; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | 0.909 |
| Cphy_1369 | Cphy_1787 | Cphy_1369 | Cphy_1787 | TIGRFAM: siroheme synthase; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | 0.996 |
| Cphy_1369 | Cphy_1788 | Cphy_1369 | Cphy_1788 | TIGRFAM: siroheme synthase; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: cth:Cthe_2529 porphobilinogen synthase; Belongs to the ALAD family. | 0.439 |
| Cphy_1369 | hemC-2 | Cphy_1369 | Cphy_1786 | TIGRFAM: siroheme synthase; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.573 |
| Cphy_1371 | Cphy_1369 | Cphy_1371 | Cphy_1369 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | TIGRFAM: siroheme synthase; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | 0.999 |
| Cphy_1371 | Cphy_1375 | Cphy_1371 | Cphy_1375 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: ckl:CKL_0727 CbiL; Belongs to the precorrin methyltransferase family. | 0.978 |
| Cphy_1371 | Cphy_1379 | Cphy_1371 | Cphy_1379 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | TIGRFAM: precorrin-6x reductase; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Precorrin-6x reductase CbiJ/CobK; KEGG: ctc:CTC00734 precorrin-6B methylase/decarboxylase cbiT/cbiE. | 0.914 |
| Cphy_1371 | Cphy_1387 | Cphy_1371 | Cphy_1387 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | Anaerobic cobalt chelatase; PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; anaerobic cobalt chelatase; KEGG: cno:NT01CX_0573 anaerobic cobalt chelatase. | 0.468 |
| Cphy_1371 | Cphy_1779 | Cphy_1371 | Cphy_1779 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | Anaerobic cobalt chelatase; PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; anaerobic cobalt chelatase; KEGG: tde:TDE2656 cobalt chelatase. | 0.453 |
| Cphy_1371 | Cphy_1785 | Cphy_1371 | Cphy_1785 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | TIGRFAM: siroheme synthase; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | 0.995 |
| Cphy_1371 | Cphy_1787 | Cphy_1371 | Cphy_1787 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | 0.964 |
| Cphy_1371 | Cphy_1788 | Cphy_1371 | Cphy_1788 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: cth:Cthe_2529 porphobilinogen synthase; Belongs to the ALAD family. | 0.977 |
| Cphy_1371 | hemA2 | Cphy_1371 | Cphy_1784 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.886 |
| Cphy_1371 | hemC-2 | Cphy_1371 | Cphy_1786 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
| Cphy_1375 | Cphy_1369 | Cphy_1375 | Cphy_1369 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: ckl:CKL_0727 CbiL; Belongs to the precorrin methyltransferase family. | TIGRFAM: siroheme synthase; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | 0.958 |