Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Cphy_1851Cytochrome c biogenesis protein transmembrane region; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; electron transport protein SCO1/SenC; cytochrome c biogenesis protein transmembrane region; Redoxin domain protein; Thioredoxin domain; KEGG: cpr:CPR_0721 cytochrome c biogenesis protein transmembrane region family. (409 aa)    
Predicted Functional Partners:
Cphy_3470
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA family protein; Rhodanese domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: drm:Dred_2967 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Belongs to the sulfur carrier protein TusA family.
  
  
 0.653
Cphy_0830
Redoxin domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; Thioredoxin domain; KEGG: dsy:DSY1195 hypothetical protein.
 
  
0.633
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.618
Cphy_2119
PFAM: cytochrome c biogenesis protein transmembrane region; Heavy metal transport/detoxification protein; KEGG: cth:Cthe_1849 heavy metal transport/detoxification protein.
     
 0.574
hisI
TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: cth:Cthe_2889 phosphoribosyl-AMP cyclohydrolase; In the C-terminal section; belongs to the PRA-PH family.
  
    0.570
Cphy_2180
Transcriptional regulator, ArsR family; PFAM: Rhodanese domain protein; regulatory protein ArsR; KEGG: mba:Mbar_A3427 putative ArsR family transcriptional regulator.
  
  
 0.560
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
    0.530
Cphy_3558
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cno:NT01CX_1854 pyruvate:ferredoxin (flavodoxin) oxidoreductase.
     
 0.525
Cphy_1850
Transcriptional regulator, HxlR family; PFAM: helix-turn-helix HxlR type; KEGG: cpr:CPR_0720 cinnamoyl ester hydrolase.
  
  
 0.522
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
    0.519
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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