STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_1877PFAM: glycoside hydrolase family 31; KEGG: bad:BAD_1599 alpha-xylosidase; Belongs to the glycosyl hydrolase 31 family. (797 aa)    
Predicted Functional Partners:
Cphy_1876
Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: cbe:Cbei_1439 regulatory protein, LacI.
       0.608
Cphy_1878
PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: csc:Csac_2452 methyl-accepting chemotaxis sensory transducer.
       0.588
Cphy_1879
PFAM: extracellular solute-binding protein family 1; KEGG: cdi:DIP0534 putative sugar-binding secreted protein.
 
     0.493
Cphy_2458
PFAM: aconitate hydratase domain protein; KEGG: dsy:DSY4204 aconitase A.
    
 
 0.484
Cphy_0208
PFAM: heat shock protein DnaJ domain protein; KEGG: cbf:CLI_0254 molecular chaperone, DnaJ family.
   
 
 0.472
Cphy_2171
PFAM: heat shock protein DnaJ domain protein.
   
 
 0.472
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 
 0.472
Cphy_3683
KEGG: cbe:Cbei_1903 fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II.
   
   0.429
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
   
   0.426
Cphy_0265
KEGG: sbl:Sbal_2840 hypothetical protein.
    
 0.419
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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