Cphy_1884 protein (Lachnoclostridium phytofermentans)

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Cphy_1884

Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (318 aa)

Predicted Functional Partners:

polA

0.589

proS

0.564

guaA

0.529

Cphy_1883

0.519

Cphy_1885

0.513

truA-2

0.448

truA-3

0.442

birA

0.433

Cphy_2202

0.431

metG

0.420

Your Current Organism:

Lachnoclostridium phytofermentans

NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cphy_1883	Cphy_1884	Cphy_1883	Cphy_1884	Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: asu:Asuc_1193 periplasmic binding protein/LacI transcriptional regulator.	Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.519
Cphy_1884	Cphy_1883	Cphy_1884	Cphy_1883	Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: asu:Asuc_1193 periplasmic binding protein/LacI transcriptional regulator.	0.519
Cphy_1884	Cphy_1885	Cphy_1884	Cphy_1885	Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	KEGG: cac:CAC1508 hypothetical protein.	0.513
Cphy_1884	Cphy_2202	Cphy_1884	Cphy_2202	Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	PFAM: phosphopantetheine-binding; KEGG: ckl:CKL_1730 polyketide synthase-related protein.	0.431
Cphy_1884	birA	Cphy_1884	Cphy_2779	Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.	0.433
Cphy_1884	guaA	Cphy_1884	Cphy_0264	Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.	0.529
Cphy_1884	metG	Cphy_1884	Cphy_0025	Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	0.420
Cphy_1884	polA	Cphy_1884	Cphy_2803	Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.589
Cphy_1884	proS	Cphy_1884	Cphy_3837	Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).	0.564
Cphy_1884	truA-2	Cphy_1884	Cphy_0879	Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	0.448
Cphy_1884	truA-3	Cphy_1884	Cphy_3634	Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	0.442
Cphy_1885	Cphy_1884	Cphy_1885	Cphy_1884	KEGG: cac:CAC1508 hypothetical protein.	Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.513
Cphy_2202	Cphy_1884	Cphy_2202	Cphy_1884	PFAM: phosphopantetheine-binding; KEGG: ckl:CKL_1730 polyketide synthase-related protein.	Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.431
Cphy_2202	birA	Cphy_2202	Cphy_2779	PFAM: phosphopantetheine-binding; KEGG: ckl:CKL_1730 polyketide synthase-related protein.	biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.	0.689
Cphy_2202	polA	Cphy_2202	Cphy_2803	PFAM: phosphopantetheine-binding; KEGG: ckl:CKL_1730 polyketide synthase-related protein.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.793
birA	Cphy_1884	Cphy_2779	Cphy_1884	biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.	Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.433
birA	Cphy_2202	Cphy_2779	Cphy_2202	biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.	PFAM: phosphopantetheine-binding; KEGG: ckl:CKL_1730 polyketide synthase-related protein.	0.689
birA	guaA	Cphy_2779	Cphy_0264	biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.	GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.	0.755
birA	metG	Cphy_2779	Cphy_0025	biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.	methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	0.628
guaA	Cphy_1884	Cphy_0264	Cphy_1884	GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.	Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.529

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