node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cphy_0499 | Cphy_1958 | Cphy_0499 | Cphy_1958 | PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; KEGG: gka:GK3152 hypothetical protein. | PFAM: Mg2 transporter protein CorA family protein; KEGG: tde:TDE1034 magnesium and cobalt transporter, putative. | 0.431 |
Cphy_1958 | Cphy_0499 | Cphy_1958 | Cphy_0499 | PFAM: Mg2 transporter protein CorA family protein; KEGG: tde:TDE1034 magnesium and cobalt transporter, putative. | PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; KEGG: gka:GK3152 hypothetical protein. | 0.431 |
Cphy_1958 | Cphy_1960 | Cphy_1958 | Cphy_1960 | PFAM: Mg2 transporter protein CorA family protein; KEGG: tde:TDE1034 magnesium and cobalt transporter, putative. | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 phosphatidylserine synthase. | 0.472 |
Cphy_1958 | Cphy_3350 | Cphy_1958 | Cphy_3350 | PFAM: Mg2 transporter protein CorA family protein; KEGG: tde:TDE1034 magnesium and cobalt transporter, putative. | KEGG: cac:CAC1655 bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain); TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein. | 0.409 |
Cphy_1958 | hisI | Cphy_1958 | Cphy_2782 | PFAM: Mg2 transporter protein CorA family protein; KEGG: tde:TDE1034 magnesium and cobalt transporter, putative. | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: cth:Cthe_2889 phosphoribosyl-AMP cyclohydrolase; In the C-terminal section; belongs to the PRA-PH family. | 0.496 |
Cphy_1958 | mprF | Cphy_1958 | Cphy_1959 | PFAM: Mg2 transporter protein CorA family protein; KEGG: tde:TDE1034 magnesium and cobalt transporter, putative. | Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.505 |
Cphy_1960 | Cphy_1958 | Cphy_1960 | Cphy_1958 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 phosphatidylserine synthase. | PFAM: Mg2 transporter protein CorA family protein; KEGG: tde:TDE1034 magnesium and cobalt transporter, putative. | 0.472 |
Cphy_1960 | Cphy_3350 | Cphy_1960 | Cphy_3350 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 phosphatidylserine synthase. | KEGG: cac:CAC1655 bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain); TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein. | 0.435 |
Cphy_1960 | mprF | Cphy_1960 | Cphy_1959 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 phosphatidylserine synthase. | Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.886 |
Cphy_3350 | Cphy_1958 | Cphy_3350 | Cphy_1958 | KEGG: cac:CAC1655 bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain); TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein. | PFAM: Mg2 transporter protein CorA family protein; KEGG: tde:TDE1034 magnesium and cobalt transporter, putative. | 0.409 |
Cphy_3350 | Cphy_1960 | Cphy_3350 | Cphy_1960 | KEGG: cac:CAC1655 bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain); TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein. | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 phosphatidylserine synthase. | 0.435 |
Cphy_3350 | hisI | Cphy_3350 | Cphy_2782 | KEGG: cac:CAC1655 bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain); TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein. | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: cth:Cthe_2889 phosphoribosyl-AMP cyclohydrolase; In the C-terminal section; belongs to the PRA-PH family. | 0.932 |
hisI | Cphy_1958 | Cphy_2782 | Cphy_1958 | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: cth:Cthe_2889 phosphoribosyl-AMP cyclohydrolase; In the C-terminal section; belongs to the PRA-PH family. | PFAM: Mg2 transporter protein CorA family protein; KEGG: tde:TDE1034 magnesium and cobalt transporter, putative. | 0.496 |
hisI | Cphy_3350 | Cphy_2782 | Cphy_3350 | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: cth:Cthe_2889 phosphoribosyl-AMP cyclohydrolase; In the C-terminal section; belongs to the PRA-PH family. | KEGG: cac:CAC1655 bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain); TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein. | 0.932 |
mprF | Cphy_1958 | Cphy_1959 | Cphy_1958 | Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | PFAM: Mg2 transporter protein CorA family protein; KEGG: tde:TDE1034 magnesium and cobalt transporter, putative. | 0.505 |
mprF | Cphy_1960 | Cphy_1959 | Cphy_1960 | Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 phosphatidylserine synthase. | 0.886 |