| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cphy_0118 | Cphy_2202 | Cphy_0118 | Cphy_2202 | KEGG: cbe:Cbei_2871 glycine betaine/L-proline ABC transporter, ATPase subunit; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: CBS domain containing protein; ABC transporter related; SMART: AAA ATPase. | PFAM: phosphopantetheine-binding; KEGG: ckl:CKL_1730 polyketide synthase-related protein. | 0.416 |
| Cphy_0118 | mprF | Cphy_0118 | Cphy_1959 | KEGG: cbe:Cbei_2871 glycine betaine/L-proline ABC transporter, ATPase subunit; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: CBS domain containing protein; ABC transporter related; SMART: AAA ATPase. | Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.414 |
| Cphy_0118 | secF | Cphy_0118 | Cphy_0716 | KEGG: cbe:Cbei_2871 glycine betaine/L-proline ABC transporter, ATPase subunit; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: CBS domain containing protein; ABC transporter related; SMART: AAA ATPase. | Protein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.442 |
| Cphy_0287 | mprF | Cphy_0287 | Cphy_1959 | PFAM: GCN5-related N-acetyltransferase; KEGG: lsl:LSL_0634 phosphinothricin N-acetyltransferase. | Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.539 |
| Cphy_0693 | mprF | Cphy_0693 | Cphy_1959 | PFAM: Endonuclease/exonuclease/phosphatase; KEGG: bfr:BF1755 hypothetical protein. | Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.523 |
| Cphy_0693 | secF | Cphy_0693 | Cphy_0716 | PFAM: Endonuclease/exonuclease/phosphatase; KEGG: bfr:BF1755 hypothetical protein. | Protein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.409 |
| Cphy_1342 | mprF | Cphy_1342 | Cphy_1959 | PFAM: GtrA family protein; KEGG: ldb:Ldb1931 teichoic acid glycosylation protein. | Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.409 |
| Cphy_1379 | mprF | Cphy_1379 | Cphy_1959 | TIGRFAM: precorrin-6x reductase; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Precorrin-6x reductase CbiJ/CobK; KEGG: ctc:CTC00734 precorrin-6B methylase/decarboxylase cbiT/cbiE. | Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.430 |
| Cphy_1958 | Cphy_1960 | Cphy_1958 | Cphy_1960 | PFAM: Mg2 transporter protein CorA family protein; KEGG: tde:TDE1034 magnesium and cobalt transporter, putative. | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 phosphatidylserine synthase. | 0.472 |
| Cphy_1958 | mprF | Cphy_1958 | Cphy_1959 | PFAM: Mg2 transporter protein CorA family protein; KEGG: tde:TDE1034 magnesium and cobalt transporter, putative. | Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.505 |
| Cphy_1960 | Cphy_1958 | Cphy_1960 | Cphy_1958 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 phosphatidylserine synthase. | PFAM: Mg2 transporter protein CorA family protein; KEGG: tde:TDE1034 magnesium and cobalt transporter, putative. | 0.472 |
| Cphy_1960 | Cphy_1961 | Cphy_1960 | Cphy_1961 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 phosphatidylserine synthase. | PFAM: phosphatidylserine decarboxylase-related; KEGG: cac:CAC0799 phosphatidylserine decarboxylase; Belongs to the phosphatidylserine decarboxylase family. | 0.993 |
| Cphy_1960 | mprF | Cphy_1960 | Cphy_1959 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 phosphatidylserine synthase. | Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.886 |
| Cphy_1961 | Cphy_1960 | Cphy_1961 | Cphy_1960 | PFAM: phosphatidylserine decarboxylase-related; KEGG: cac:CAC0799 phosphatidylserine decarboxylase; Belongs to the phosphatidylserine decarboxylase family. | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 phosphatidylserine synthase. | 0.993 |
| Cphy_1961 | mprF | Cphy_1961 | Cphy_1959 | PFAM: phosphatidylserine decarboxylase-related; KEGG: cac:CAC0799 phosphatidylserine decarboxylase; Belongs to the phosphatidylserine decarboxylase family. | Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.760 |
| Cphy_2202 | Cphy_0118 | Cphy_2202 | Cphy_0118 | PFAM: phosphopantetheine-binding; KEGG: ckl:CKL_1730 polyketide synthase-related protein. | KEGG: cbe:Cbei_2871 glycine betaine/L-proline ABC transporter, ATPase subunit; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: CBS domain containing protein; ABC transporter related; SMART: AAA ATPase. | 0.416 |
| Cphy_2202 | mprF | Cphy_2202 | Cphy_1959 | PFAM: phosphopantetheine-binding; KEGG: ckl:CKL_1730 polyketide synthase-related protein. | Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.466 |
| mprF | Cphy_0118 | Cphy_1959 | Cphy_0118 | Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | KEGG: cbe:Cbei_2871 glycine betaine/L-proline ABC transporter, ATPase subunit; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: CBS domain containing protein; ABC transporter related; SMART: AAA ATPase. | 0.414 |
| mprF | Cphy_0287 | Cphy_1959 | Cphy_0287 | Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | PFAM: GCN5-related N-acetyltransferase; KEGG: lsl:LSL_0634 phosphinothricin N-acetyltransferase. | 0.539 |
| mprF | Cphy_0693 | Cphy_1959 | Cphy_0693 | Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | PFAM: Endonuclease/exonuclease/phosphatase; KEGG: bfr:BF1755 hypothetical protein. | 0.523 |