STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_2195PFAM: integrase family protein; KEGG: cdf:CD1932 putative tyrosine recombinase; Belongs to the 'phage' integrase family. (350 aa)    
Predicted Functional Partners:
Cphy_3788
Hypothetical protein.
  
     0.619
Cphy_0248
KEGG: tte:TTE0490 predicted amidophosphoribosyltransferases.
  
    0.573
Cphy_0423
Hypothetical protein.
  
     0.532
Cphy_3931
Hypothetical protein.
  
     0.526
Cphy_2372
PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: csc:Csac_1869 peptidoglycan glycosyltransferase.
  
   
 0.500
Cphy_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
   
 0.496
Cphy_3460
Hypothetical protein.
  
     0.491
Cphy_2363
Hypothetical protein; KEGG: tte:TTE1601 membrane-fusion protein.
  
     0.490
Cphy_3552
Hypothetical protein.
  
     0.468
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.464
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.