| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cphy_0426 | Cphy_2352 | Cphy_0426 | Cphy_2352 | KEGG: lsl:LSL_0313 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. | KEGG: cbe:Cbei_4207 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.971 |
| Cphy_0426 | Cphy_3600 | Cphy_0426 | Cphy_3600 | KEGG: lsl:LSL_0313 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. | KEGG: csc:Csac_0991 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.976 |
| Cphy_0426 | Cphy_3603 | Cphy_0426 | Cphy_3603 | KEGG: lsl:LSL_0313 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: csc:Csac_0993 homoserine dehydrogenase. | 0.986 |
| Cphy_0426 | argG | Cphy_0426 | Cphy_1931 | KEGG: lsl:LSL_0313 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. | PFAM: argininosuccinate synthase; KEGG: cth:Cthe_0179 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.566 |
| Cphy_0426 | hisI | Cphy_0426 | Cphy_2782 | KEGG: lsl:LSL_0313 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: cth:Cthe_2889 phosphoribosyl-AMP cyclohydrolase; In the C-terminal section; belongs to the PRA-PH family. | 0.794 |
| Cphy_0426 | purA | Cphy_0426 | Cphy_3037 | KEGG: lsl:LSL_0313 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.431 |
| Cphy_2352 | Cphy_0426 | Cphy_2352 | Cphy_0426 | KEGG: cbe:Cbei_4207 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | KEGG: lsl:LSL_0313 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.971 |
| Cphy_2352 | Cphy_2936 | Cphy_2352 | Cphy_2936 | KEGG: cbe:Cbei_4207 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | KEGG: cth:Cthe_0556 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase. | 0.885 |
| Cphy_2352 | Cphy_3413 | Cphy_2352 | Cphy_3413 | KEGG: cbe:Cbei_4207 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | TIGRFAM: L-asparaginase, type I; PFAM: Asparaginase/glutaminase; KEGG: lac:LBA1687 L-asparaginase. | 0.841 |
| Cphy_2352 | Cphy_3530 | Cphy_2352 | Cphy_3530 | KEGG: cbe:Cbei_4207 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | PFAM: aminotransferase class I and II; KEGG: dsy:DSY1222 hypothetical protein. | 0.834 |
| Cphy_2352 | Cphy_3600 | Cphy_2352 | Cphy_3600 | KEGG: cbe:Cbei_4207 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | KEGG: csc:Csac_0991 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.900 |
| Cphy_2352 | Cphy_3603 | Cphy_2352 | Cphy_3603 | KEGG: cbe:Cbei_4207 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: csc:Csac_0993 homoserine dehydrogenase. | 0.867 |
| Cphy_2352 | argG | Cphy_2352 | Cphy_1931 | KEGG: cbe:Cbei_4207 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | PFAM: argininosuccinate synthase; KEGG: cth:Cthe_0179 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.876 |
| Cphy_2352 | hisI | Cphy_2352 | Cphy_2782 | KEGG: cbe:Cbei_4207 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: cth:Cthe_2889 phosphoribosyl-AMP cyclohydrolase; In the C-terminal section; belongs to the PRA-PH family. | 0.950 |
| Cphy_2352 | metAA | Cphy_2352 | Cphy_2925 | KEGG: cbe:Cbei_4207 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.894 |
| Cphy_2352 | purA | Cphy_2352 | Cphy_3037 | KEGG: cbe:Cbei_4207 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.827 |
| Cphy_2936 | Cphy_2352 | Cphy_2936 | Cphy_2352 | KEGG: cth:Cthe_0556 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase. | KEGG: cbe:Cbei_4207 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.885 |
| Cphy_2936 | Cphy_3413 | Cphy_2936 | Cphy_3413 | KEGG: cth:Cthe_0556 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase. | TIGRFAM: L-asparaginase, type I; PFAM: Asparaginase/glutaminase; KEGG: lac:LBA1687 L-asparaginase. | 0.922 |
| Cphy_2936 | Cphy_3530 | Cphy_2936 | Cphy_3530 | KEGG: cth:Cthe_0556 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase. | PFAM: aminotransferase class I and II; KEGG: dsy:DSY1222 hypothetical protein. | 0.908 |
| Cphy_2936 | Cphy_3600 | Cphy_2936 | Cphy_3600 | KEGG: cth:Cthe_0556 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase. | KEGG: csc:Csac_0991 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.869 |