STRINGSTRING
murD protein (Lachnoclostridium phytofermentans) - STRING interaction network
"murD" - UDP-N-acetylmuramoylalanine--D-glutamate ligase in Lachnoclostridium phytofermentans
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA); Belongs to the MurCDEF family (454 aa)    
Predicted Functional Partners:
murE
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the MurCDEF family. MurE subfamily (493 aa)
 
  0.993
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis (270 aa)
 
 
  0.982
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family (469 aa)
0.975
Cphy_2474
PFAM- cell cycle protein; KEGG- csc-Csac_0924 cell division protein FtsW; Belongs to the SEDS family (376 aa)
   
  0.939
Cphy_2473
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily (418 aa)
 
 
  0.888
Cphy_3351
PFAM- glycosyl transferase family 4; KEGG- tde-TDE2249 phospho-N-acetylmuramoyl-pentapeptide-transferase (320 aa)
 
   
  0.870
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily (355 aa)
   
  0.858
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily (507 aa)
   
0.846
Cphy_2472
KEGG- cbh-CLC_1498 cell division protein FtsQ (249 aa)
   
   
  0.844
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation (310 aa)
 
 
  0.829
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans, Lachnoclostridium phytofermentans ISDg
Server load: low (11%) [HD]