STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glgAGlycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (478 aa)    
Predicted Functional Partners:
Cphy_2348
Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
 
  
 0.989
Cphy_2349
KEGG: ftw:FTW_1655 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 77.
 
 
 0.985
Cphy_2331
Pullulanase, type I; KEGG: cpe:CPE1552 pullulanase; TIGRFAM: pullulanase, type I; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; Belongs to the glycosyl hydrolase 13 family.
 
  
 0.903
Cphy_2304
KEGG: cbe:Cbei_4135 pullulanase, type I; TIGRFAM: pullulanase, type I; PFAM: glycoside hydrolase family 13 domain protein; pullanase-associated protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; Belongs to the glycosyl hydrolase 13 family.
 
  
 0.902
Cphy_3925
PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase_; KEGG: cth:Cthe_0423 iron-containing alcohol dehydrogenase.
  
  
 0.795
Cphy_2350
Alpha amylase catalytic region; PFAM: glycoside hydrolase family 13 domain protein Ig domain protein region domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: gtn:GTNG_0610 neopullulanase; Belongs to the glycosyl hydrolase 13 family.
 
  
 0.728
Cphy_2497
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
     
 0.712
Cphy_0465
KEGG: bha:BH0709 hypothetical protein.
   
    0.641
hrcA
Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
 
   
 0.634
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
  
 0.606
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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