STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_2539Prephenate dehydrogenase; PFAM: amino acid-binding ACT domain protein; Prephenate dehydrogenase; KEGG: cth:Cthe_1796 prephenate dehydrogenase. (369 aa)    
Predicted Functional Partners:
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
 0.993
Cphy_1345
PFAM: prephenate dehydratase; Chorismate mutase; KEGG: ckl:CKL_0789 PheA.
 0.987
hisC
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: llm:llmg_1298 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.975
Cphy_2538
TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: cth:Cthe_1795 phospho-2-dehydro-3-deoxyheptonate aldolase.
 
 
 0.955
Cphy_3530
PFAM: aminotransferase class I and II; KEGG: dsy:DSY1222 hypothetical protein.
  
 
 0.914
Cphy_3604
PFAM: amino acid-binding ACT domain protein; KEGG: amt:Amet_0565 amino acid-binding ACT; Belongs to the UPF0735 family.
     
 0.909
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 
 0.865
cmk
KEGG: csc:Csac_1889 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
 
  
 0.831
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
  
 0.763
Cphy_1111
PFAM: aminotransferase class I and II; KEGG: cpe:CPE1040 probable Thr-phospho decarboxylase.
  
  
 0.762
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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