| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cphy_0127 | Cphy_0210 | Cphy_0127 | Cphy_0210 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: cth:Cthe_2618 stage III sporulation protein D, SpoIIID. | 0.872 |
| Cphy_0127 | Cphy_0476 | Cphy_0127 | Cphy_0476 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: amt:Amet_2212 anti-sigma-factor antagonist. | 0.804 |
| Cphy_0127 | Cphy_0478 | Cphy_0127 | Cphy_0478 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | RNA polymerase, sigma 28 subunit, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.750 |
| Cphy_0127 | Cphy_0479 | Cphy_0127 | Cphy_0479 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein; KEGG: drm:Dred_1106 SpoVA protein. | 0.777 |
| Cphy_0127 | Cphy_0480 | Cphy_0127 | Cphy_0480 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; KEGG: amt:Amet_2220 stage V sporulation AD family protein. | 0.832 |
| Cphy_0127 | Cphy_2316 | Cphy_0127 | Cphy_2316 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | PFAM: Stage II sporulation P family protein; KEGG: cth:Cthe_1328 stage II sporulation P. | 0.753 |
| Cphy_0127 | Cphy_2498 | Cphy_0127 | Cphy_2498 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | KEGG: amt:Amet_2512 peptidase S55, sporulation stage IV, protein B; TIGRFAM: stage IV sporulation protein B; PFAM: peptidase S55 SpoIVB; SMART: PDZ/DHR/GLGF domain protein. | 0.773 |
| Cphy_0127 | Cphy_2587 | Cphy_0127 | Cphy_2587 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: csc:Csac_1744 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | 0.627 |
| Cphy_0127 | Cphy_3792 | Cphy_0127 | Cphy_3792 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R; KEGG: cbh:CLC_0174 stage II sporulation protein R. | 0.837 |
| Cphy_0127 | spoIIAB | Cphy_0127 | Cphy_0477 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.858 |
| Cphy_0210 | Cphy_0127 | Cphy_0210 | Cphy_0127 | TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: cth:Cthe_2618 stage III sporulation protein D, SpoIIID. | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | 0.872 |
| Cphy_0210 | Cphy_0476 | Cphy_0210 | Cphy_0476 | TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: cth:Cthe_2618 stage III sporulation protein D, SpoIIID. | Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: amt:Amet_2212 anti-sigma-factor antagonist. | 0.847 |
| Cphy_0210 | Cphy_0478 | Cphy_0210 | Cphy_0478 | TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: cth:Cthe_2618 stage III sporulation protein D, SpoIIID. | RNA polymerase, sigma 28 subunit, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.730 |
| Cphy_0210 | Cphy_0479 | Cphy_0210 | Cphy_0479 | TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: cth:Cthe_2618 stage III sporulation protein D, SpoIIID. | TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein; KEGG: drm:Dred_1106 SpoVA protein. | 0.809 |
| Cphy_0210 | Cphy_0480 | Cphy_0210 | Cphy_0480 | TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: cth:Cthe_2618 stage III sporulation protein D, SpoIIID. | TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; KEGG: amt:Amet_2220 stage V sporulation AD family protein. | 0.799 |
| Cphy_0210 | Cphy_2316 | Cphy_0210 | Cphy_2316 | TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: cth:Cthe_2618 stage III sporulation protein D, SpoIIID. | PFAM: Stage II sporulation P family protein; KEGG: cth:Cthe_1328 stage II sporulation P. | 0.854 |
| Cphy_0210 | Cphy_2498 | Cphy_0210 | Cphy_2498 | TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: cth:Cthe_2618 stage III sporulation protein D, SpoIIID. | KEGG: amt:Amet_2512 peptidase S55, sporulation stage IV, protein B; TIGRFAM: stage IV sporulation protein B; PFAM: peptidase S55 SpoIVB; SMART: PDZ/DHR/GLGF domain protein. | 0.798 |
| Cphy_0210 | Cphy_2587 | Cphy_0210 | Cphy_2587 | TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: cth:Cthe_2618 stage III sporulation protein D, SpoIIID. | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: csc:Csac_1744 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | 0.604 |
| Cphy_0210 | Cphy_3792 | Cphy_0210 | Cphy_3792 | TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: cth:Cthe_2618 stage III sporulation protein D, SpoIIID. | TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R; KEGG: cbh:CLC_0174 stage II sporulation protein R. | 0.864 |
| Cphy_0210 | spoIIAB | Cphy_0210 | Cphy_0477 | TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: cth:Cthe_2618 stage III sporulation protein D, SpoIIID. | Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.865 |