Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_2612PFAM: putative stage IV sporulation YqfD; KEGG: bcy:Bcer98_3032 putative stage IV sporulation YqfD. (412 aa)    
Predicted Functional Partners:
Cphy_2613
PFAM: protein of unknown function DUF1429; KEGG: amt:Amet_3035 protein of unknown function DUF1429.
 
  
 0.990
Cphy_1324
PFAM: nucleoside recognition domain protein; KEGG: tte:TTE1484 hypothetical protein.
 
   
 0.880
Cphy_0135
TIGRFAM: sporulation protein YabP; PFAM: YabP family protein; KEGG: cth:Cthe_2659 YabP-like protein.
 
   
 0.862
Cphy_2611
PFAM: PhoH family protein; KEGG: tte:TTE0970 Phosphate starvation-inducible protein PhoH, predicted ATPase.
       0.856
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.846
Cphy_2470
Peptidase U4 sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
   
 0.838
Cphy_3792
TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R; KEGG: cbh:CLC_0174 stage II sporulation protein R.
  
  
 0.824
Cphy_2316
PFAM: Stage II sporulation P family protein; KEGG: cth:Cthe_1328 stage II sporulation P.
  
   
 0.819
Cphy_0210
TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: cth:Cthe_2618 stage III sporulation protein D, SpoIIID.
  
   
 0.812
Cphy_2524
TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase; KEGG: pth:PTH_1166 hypothetical protein.
  
  
 0.798
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.