Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Cphy_2742Transcriptional regulator, LacI family; Involved in control of pectin and galacturonic acid metabolism. Probably represses a comprehensive set of pectin fermentation genes by binding a conserved palindrome at or downstream of their transcription start site to block transcription. In the presence of galacturonic acid may activate transcription of acetate synthesis and other aspects of carbon metabolism. (333 aa)    
Predicted Functional Partners:
Cphy_1454
PFAM: regulatory protein LacI; KEGG: cpf:CPF_1547 transcriptional regulator, LacI family.
  
     0.766
Cphy_1012
PFAM: regulatory protein GntR HTH; KEGG: gtn:GTNG_1824 transcriptional regulator.
  
     0.762
Cphy_1060
PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: smd:Smed_5753 regulatory protein LacI.
 
    0.750
uxaC
PFAM: Glucuronate isomerase; KEGG: cbe:Cbei_1832 glucuronate isomerase.
  
  
 0.594
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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