STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_2742Transcriptional regulator, LacI family; Involved in control of pectin and galacturonic acid metabolism. Probably represses a comprehensive set of pectin fermentation genes by binding a conserved palindrome at or downstream of their transcription start site to block transcription. In the presence of galacturonic acid may activate transcription of acetate synthesis and other aspects of carbon metabolism. (333 aa)    
Predicted Functional Partners:
Cphy_1454
PFAM: regulatory protein LacI; KEGG: cpf:CPF_1547 transcriptional regulator, LacI family.
  
     0.766
Cphy_1012
PFAM: regulatory protein GntR HTH; KEGG: gtn:GTNG_1824 transcriptional regulator.
  
     0.762
Cphy_1060
PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: smd:Smed_5753 regulatory protein LacI.
 
  
 0.755
uxaC
PFAM: Glucuronate isomerase; KEGG: cbe:Cbei_1832 glucuronate isomerase.
  
  
 0.599
Cphy_1326
KEGG: cth:Cthe_1029 phosphate acetyltransferase; TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase.
      
 0.520
Cphy_0367
PFAM: alpha/beta hydrolase fold; KEGG: tde:TDE2146 hydrolase, alpha/beta fold family.
      
 0.504
Cphy_2919
PFAM: protein of unknown function DUF1565; KEGG: sde:Sde_2946 hypothetical protein.
      
 0.504
Cphy_3869
PFAM: Fibronectin type III domain protein; KEGG: bha:BH0494 exopolygalacturonate lyase.
      
 0.504
Cphy_0741
TIGRFAM: pyruvate kinase; PFAM: PEP-utilising protein mobile region; Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: csc:Csac_1831 pyruvate kinase; Belongs to the pyruvate kinase family.
    
 
 0.418
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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