STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_2820Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (250 aa)    
Predicted Functional Partners:
Cphy_2823
KEGG: bcy:Bcer98_0431 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: pyruvate formate-lyase PFL.
  
 0.960
Cphy_2821
PFAM: formate C-acetyltransferase glycine radical; KEGG: bcy:Bcer98_0431 formate acetyltransferase.
 
  
 0.943
Cphy_1174
KEGG: cno:NT01CX_0498 pyruvate formate-lyase; TIGRFAM: pyruvate formate-lyase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL.
 
  
 0.842
cutC
Formate C-acetyltransferase; Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde. Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.
 
  
 0.740
Cphy_1106
KEGG: cpr:CPR_1109 hypothetical protein.
   
    0.723
Cphy_3925
PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase_; KEGG: cth:Cthe_0423 iron-containing alcohol dehydrogenase.
  
  
 0.605
Cphy_3558
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cno:NT01CX_1854 pyruvate:ferredoxin (flavodoxin) oxidoreductase.
     
 0.581
Cphy_2819
PFAM: peptidase A24A prepilin type IV; peptidase A24A domain protein; KEGG: tte:TTE1266 leader peptidase (prepilin peptidase) / N-methyltransferase.
       0.523
Cphy_0603
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cdf:CD2682 pyruvate-flavodoxin oxidoreductase.
     
 0.496
Cphy_1029
PFAM: iron-containing alcohol dehydrogenase; KEGG: tva:TVAG_422780 alcohol dehydrogensae, putative Pfam: Fe-ADH DHQ_synthase PROSITE: COPPER_BLUE ADH_IRON_1.
  
  
 0.410
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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