STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tdkPFAM: thymidine kinase; KEGG: hdu:HD1473 thymidine kinase. (186 aa)    
Predicted Functional Partners:
Cphy_3038
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
   
 
 0.959
Cphy_2591
KEGG: cno:NT01CX_1499 pyrimidine-nucleoside phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain.
 
  
 0.942
Cphy_0754
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
  
 0.937
Cphy_0189
PFAM: CMP/dCMP deaminase zinc-binding; KEGG: cbe:Cbei_0409 CMP/dCMP deaminase, zinc-binding.
  
 
 0.927
Cphy_3434
PFAM: metallophosphoesterase; KEGG: sak:SAK_1901 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic precursor protein.
 
  
  0.927
Cphy_1253
PFAM: metallophosphoesterase; KEGG: bcl:ABC0966 nucleotidase; Belongs to the 5'-nucleotidase family.
 
  
  0.922
Cphy_0261
KEGG: ppd:Ppro_1070 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
 
  
  0.915
Cphy_0132
TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: chy:CHY_0204 tetrapyrrole methylase family protein/MazG family protein.
     
  0.900
Cphy_1933
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     
  0.900
Cphy_1981
5'-nucleotidase; PFAM: 5-nucleotidase; KEGG: har:HEAR0649 putative 5'-nucleotidase.
     
  0.900
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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