STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_3124PFAM: GCN5-related N-acetyltransferase; KEGG: ckl:CKL_3663 hypothetical protein. (153 aa)    
Predicted Functional Partners:
Cphy_3125
PFAM: GCN5-related N-acetyltransferase; KEGG: bld:BLi02251 hypothetical protein.
  
    0.477
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.468
Cphy_0296
DNA topoisomerase (ATP-hydrolyzing); KEGG: gka:GK0005 DNA gyrase subunit B; PFAM: DNA gyrase subunit B domain protein; ATP-binding region ATPase domain protein; TOPRIM domain protein; DNA topoisomerase type IIA subunit B region 2 domain protein; SMART: DNA topoisomerase II.
   
 
 0.468
Cphy_2948
KEGG: ckl:CKL_3246 hypothetical protein.
  
 
 0.410
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.