STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
Cphy_3172Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (458 aa)    
Predicted Functional Partners:
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 0.997
trpC
PFAM: Indole-3-glycerol phosphate synthase; KEGG: msi:Msm_1143 indole-3-glycerol phosphate synthase, TrpC; Belongs to the TrpC family.
  
 
 0.939
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 
0.919
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.909
Cphy_2441
TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: cbe:Cbei_1562 threonine dehydratase.
     
 0.901
Cphy_1459
KEGG: amt:Amet_2318 L-serine dehydratase, iron-sulfur-dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain.
     
  0.900
Cphy_1460
TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: amino acid-binding ACT domain protein; serine dehydratase beta chain; KEGG: tte:TTE1008 L-serine deaminase.
     
 0.900
Cphy_1960
PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 phosphatidylserine synthase.
     
  0.900
Cphy_3112
PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: cbe:Cbei_2232 serine dehydratase alpha chain.
     
  0.900
Cphy_0469
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: dsy:DSY4986 hypothetical protein.
     
  0.800
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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