STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Cphy_3222Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (342 aa)    
Predicted Functional Partners:
Cphy_3223
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
 0.999
cmk
KEGG: csc:Csac_1889 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
    
 0.923
adk
Nucleoside-triphosphate--adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.921
Cphy_3915
SMART: guanylate kinase/L-type calcium channel region; KEGG: cpr:CPR_2447 guanylate kinase-like protein.
   
 
 0.910
Cphy_0548
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
   
 
 0.903
Cphy_3839
Cytidylate kinase-like protein; KEGG: msi:Msm_0734 cytidylate kinase, Cmk.
     
  0.900
Cphy_0739
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: dsy:DSY2429 hypothetical protein; Belongs to the thioredoxin family.
  
 
 0.544
Cphy_3919
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: sat:SYN_00045 thioredoxin; Belongs to the thioredoxin family.
  
 
 0.544
Cphy_3048
Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
     
 0.498
Cphy_0535
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: tde:TDE1331 anaerobic ribonucleoside triphosphate reductase.
  
  
 0.481
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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