| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cphy_0011 | Cphy_1228 | Cphy_0011 | Cphy_1228 | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cbe:Cbei_4356 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cth:Cthe_1560 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | 0.907 |
| Cphy_0011 | Cphy_3325 | Cphy_0011 | Cphy_3325 | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cbe:Cbei_4356 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | TIGRFAM: serine O-acetyltransferase; KEGG: csc:Csac_0707 serine O-acetyltransferase. | 0.993 |
| Cphy_0011 | cysS | Cphy_0011 | Cphy_3324 | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cbe:Cbei_4356 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; KEGG: cdf:CD0052 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.759 |
| Cphy_1228 | Cphy_0011 | Cphy_1228 | Cphy_0011 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cth:Cthe_1560 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cbe:Cbei_4356 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.907 |
| Cphy_1228 | Cphy_3325 | Cphy_1228 | Cphy_3325 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cth:Cthe_1560 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | TIGRFAM: serine O-acetyltransferase; KEGG: csc:Csac_0707 serine O-acetyltransferase. | 0.991 |
| Cphy_1228 | cysS | Cphy_1228 | Cphy_3324 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cth:Cthe_1560 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; KEGG: cdf:CD0052 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.903 |
| Cphy_1459 | Cphy_1460 | Cphy_1459 | Cphy_1460 | KEGG: amt:Amet_2318 L-serine dehydratase, iron-sulfur-dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain. | TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: amino acid-binding ACT domain protein; serine dehydratase beta chain; KEGG: tte:TTE1008 L-serine deaminase. | 0.999 |
| Cphy_1459 | Cphy_2441 | Cphy_1459 | Cphy_2441 | KEGG: amt:Amet_2318 L-serine dehydratase, iron-sulfur-dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain. | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: cbe:Cbei_1562 threonine dehydratase. | 0.915 |
| Cphy_1459 | Cphy_3112 | Cphy_1459 | Cphy_3112 | KEGG: amt:Amet_2318 L-serine dehydratase, iron-sulfur-dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain. | PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: cbe:Cbei_2232 serine dehydratase alpha chain. | 0.919 |
| Cphy_1459 | Cphy_3325 | Cphy_1459 | Cphy_3325 | KEGG: amt:Amet_2318 L-serine dehydratase, iron-sulfur-dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain. | TIGRFAM: serine O-acetyltransferase; KEGG: csc:Csac_0707 serine O-acetyltransferase. | 0.910 |
| Cphy_1459 | Cphy_3603 | Cphy_1459 | Cphy_3603 | KEGG: amt:Amet_2318 L-serine dehydratase, iron-sulfur-dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: csc:Csac_0993 homoserine dehydrogenase. | 0.806 |
| Cphy_1459 | glyA | Cphy_1459 | Cphy_3274 | KEGG: amt:Amet_2318 L-serine dehydratase, iron-sulfur-dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.953 |
| Cphy_1460 | Cphy_1459 | Cphy_1460 | Cphy_1459 | TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: amino acid-binding ACT domain protein; serine dehydratase beta chain; KEGG: tte:TTE1008 L-serine deaminase. | KEGG: amt:Amet_2318 L-serine dehydratase, iron-sulfur-dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain. | 0.999 |
| Cphy_1460 | Cphy_2441 | Cphy_1460 | Cphy_2441 | TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: amino acid-binding ACT domain protein; serine dehydratase beta chain; KEGG: tte:TTE1008 L-serine deaminase. | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: cbe:Cbei_1562 threonine dehydratase. | 0.924 |
| Cphy_1460 | Cphy_3112 | Cphy_1460 | Cphy_3112 | TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: amino acid-binding ACT domain protein; serine dehydratase beta chain; KEGG: tte:TTE1008 L-serine deaminase. | PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: cbe:Cbei_2232 serine dehydratase alpha chain. | 0.988 |
| Cphy_1460 | Cphy_3325 | Cphy_1460 | Cphy_3325 | TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: amino acid-binding ACT domain protein; serine dehydratase beta chain; KEGG: tte:TTE1008 L-serine deaminase. | TIGRFAM: serine O-acetyltransferase; KEGG: csc:Csac_0707 serine O-acetyltransferase. | 0.910 |
| Cphy_1460 | Cphy_3603 | Cphy_1460 | Cphy_3603 | TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: amino acid-binding ACT domain protein; serine dehydratase beta chain; KEGG: tte:TTE1008 L-serine deaminase. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: csc:Csac_0993 homoserine dehydrogenase. | 0.806 |
| Cphy_1460 | glyA | Cphy_1460 | Cphy_3274 | TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: amino acid-binding ACT domain protein; serine dehydratase beta chain; KEGG: tte:TTE1008 L-serine deaminase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.965 |
| Cphy_2441 | Cphy_1459 | Cphy_2441 | Cphy_1459 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: cbe:Cbei_1562 threonine dehydratase. | KEGG: amt:Amet_2318 L-serine dehydratase, iron-sulfur-dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain. | 0.915 |
| Cphy_2441 | Cphy_1460 | Cphy_2441 | Cphy_1460 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: cbe:Cbei_1562 threonine dehydratase. | TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: amino acid-binding ACT domain protein; serine dehydratase beta chain; KEGG: tte:TTE1008 L-serine deaminase. | 0.924 |