STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_3369PFAM: heat shock protein Hsp90; KEGG: cth:Cthe_0550 heat shock protein HSP90. (677 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.998
Cphy_3927
Mn2+-dependent serine/threonine protein kinase; PFAM: aminoglycoside phosphotransferase; KEGG: cth:Cthe_0424 aminoglycoside phosphotransferase.
   
 0.985
Cphy_0265
KEGG: sbl:Sbal_2840 hypothetical protein.
  
 0.976
Cphy_0208
PFAM: heat shock protein DnaJ domain protein; KEGG: cbf:CLI_0254 molecular chaperone, DnaJ family.
  
 0.975
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 0.975
Cphy_1188
Peptidase S41; PFAM: TPR repeat-containing protein; peptidase S41; RDD domain containing protein; Tetratricopeptide TPR_3; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cth:Cthe_2680 peptidase S41.
  
 0.972
Cphy_1356
PFAM: beta-lactamase domain protein; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: mbu:Mbur_2318 tetratricopeptide protein.
 
 0.968
Cphy_2171
PFAM: heat shock protein DnaJ domain protein.
  
 0.964
Cphy_3465
Hypothetical protein; KEGG: sth:STH2197 putative S-layer associated protein.
 
 0.953
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 0.949
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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