Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
addBATP-dependent nuclease subunit B; The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity. (1171 aa)    
Predicted Functional Partners:
addA
Recombination helicase AddA; The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily.
 
 
 0.999
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
  
 0.753
Cphy_1246
PFAM: SMC domain protein; KEGG: ctc:CTC00579 exonuclease sbcC.
 
  
 0.647
Cphy_3520
PFAM: protein of unknown function DUF633; KEGG: cac:CAC1302 predicted SAM-dependent methyltransferase.
 
     0.599
Cphy_3425
Hypothetical protein.
       0.580
recX
Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family.
 
   
 0.543
Cphy_3422
Hypothetical protein; KEGG: cth:Cthe_1856 small acid-soluble spore protein beta.
       0.489
Cphy_3421
PFAM: diacylglycerol kinase catalytic region; KEGG: oih:OB0767 hypothetical protein.
       0.447
pheT
KEGG: cth:Cthe_0215 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
  
    0.442
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
     
 0.439
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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