STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_3463PFAM: UvrB/UvrC protein; KEGG: csc:Csac_2369 UvrB/UvrC protein. (173 aa)    
Predicted Functional Partners:
Cphy_3462
PFAM: ATP:guanido phosphotransferase; KEGG: cth:Cthe_1790 ATP:guanido phosphotransferase.
 
 
 0.999
Cphy_3461
PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: cth:Cthe_1789 ATPase AAA-2; Belongs to the ClpA/ClpB family.
 
  
 0.927
Cphy_3464
PFAM: regulatory protein GntR HTH; KEGG: swo:Swol_1390 transcriptional regulator, GntR family.
       0.788
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
  
 0.705
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
    0.682
Cphy_3465
Hypothetical protein; KEGG: sth:STH2197 putative S-layer associated protein.
 
     0.537
Cphy_3746
PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: sha:SH0920 putative low molecular weight protein-tyrosine-phosphatase.
  
  
 0.479
Cphy_3466
PFAM: SH3 type 3 domain protein; SMART: SH3 domain protein; KEGG: cpf:CPF_1439 mannosyl-glycoprotein endo-beta-N-acetylglucosamidase domain protein, possible enterotoxin.
 
     0.438
Cphy_0050
TIGRFAM: sporulation protein YyaC; PFAM: protein of unknown function DUF1256; KEGG: cth:Cthe_2165 protein of unknown function DUF1256.
  
     0.421
clpP
ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.409
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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