node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cphy_0318 | Cphy_3043 | Cphy_0318 | Cphy_3043 | KEGG: sfu:Sfum_0268 amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: cth:Cthe_0741 adenylosuccinate lyase. | 0.874 |
Cphy_0318 | Cphy_3350 | Cphy_0318 | Cphy_3350 | KEGG: sfu:Sfum_0268 amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | KEGG: cac:CAC1655 bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain); TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein. | 0.989 |
Cphy_0318 | guaB | Cphy_0318 | Cphy_3287 | KEGG: sfu:Sfum_0268 amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.830 |
Cphy_0318 | purC | Cphy_0318 | Cphy_3045 | KEGG: sfu:Sfum_0268 amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | KEGG: csc:Csac_1999 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | 0.885 |
Cphy_0318 | purD | Cphy_0318 | Cphy_3467 | KEGG: sfu:Sfum_0268 amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | KEGG: cth:Cthe_1245 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | 0.989 |
Cphy_0318 | purE | Cphy_0318 | Cphy_3471 | KEGG: sfu:Sfum_0268 amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.896 |
Cphy_0318 | purF | Cphy_0318 | Cphy_3044 | KEGG: sfu:Sfum_0268 amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.915 |
Cphy_0318 | purH | Cphy_0318 | Cphy_0643 | KEGG: sfu:Sfum_0268 amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | KEGG: cth:Cthe_1246 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.872 |
Cphy_0318 | purM | Cphy_0318 | Cphy_3469 | KEGG: sfu:Sfum_0268 amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | KEGG: btl:BALH_0290 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. | 0.920 |
Cphy_0318 | purN | Cphy_0318 | Cphy_3468 | KEGG: sfu:Sfum_0268 amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.867 |
Cphy_3043 | Cphy_0318 | Cphy_3043 | Cphy_0318 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: cth:Cthe_0741 adenylosuccinate lyase. | KEGG: sfu:Sfum_0268 amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.874 |
Cphy_3043 | Cphy_3350 | Cphy_3043 | Cphy_3350 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: cth:Cthe_0741 adenylosuccinate lyase. | KEGG: cac:CAC1655 bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain); TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein. | 0.992 |
Cphy_3043 | guaB | Cphy_3043 | Cphy_3287 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: cth:Cthe_0741 adenylosuccinate lyase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.917 |
Cphy_3043 | purC | Cphy_3043 | Cphy_3045 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: cth:Cthe_0741 adenylosuccinate lyase. | KEGG: csc:Csac_1999 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | 0.998 |
Cphy_3043 | purD | Cphy_3043 | Cphy_3467 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: cth:Cthe_0741 adenylosuccinate lyase. | KEGG: cth:Cthe_1245 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | 0.971 |
Cphy_3043 | purE | Cphy_3043 | Cphy_3471 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: cth:Cthe_0741 adenylosuccinate lyase. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.954 |
Cphy_3043 | purF | Cphy_3043 | Cphy_3044 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: cth:Cthe_0741 adenylosuccinate lyase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.939 |
Cphy_3043 | purH | Cphy_3043 | Cphy_0643 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: cth:Cthe_0741 adenylosuccinate lyase. | KEGG: cth:Cthe_1246 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.997 |
Cphy_3043 | purM | Cphy_3043 | Cphy_3469 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: cth:Cthe_0741 adenylosuccinate lyase. | KEGG: btl:BALH_0290 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. | 0.913 |
Cphy_3043 | purN | Cphy_3043 | Cphy_3468 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: cth:Cthe_0741 adenylosuccinate lyase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.907 |