| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cphy_0312 | Cphy_3485 | Cphy_0312 | Cphy_3485 | Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. | TIGRFAM: peptidase T-like protein; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ctc:CTC00423 peptidase T. | 0.400 |
| Cphy_0312 | guaB | Cphy_0312 | Cphy_3287 | Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.868 |
| Cphy_2530 | Cphy_3485 | Cphy_2530 | Cphy_3485 | Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase. | TIGRFAM: peptidase T-like protein; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ctc:CTC00423 peptidase T. | 0.458 |
| Cphy_2530 | guaB | Cphy_2530 | Cphy_3287 | Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.828 |
| Cphy_3485 | Cphy_0312 | Cphy_3485 | Cphy_0312 | TIGRFAM: peptidase T-like protein; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ctc:CTC00423 peptidase T. | Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. | 0.400 |
| Cphy_3485 | Cphy_2530 | Cphy_3485 | Cphy_2530 | TIGRFAM: peptidase T-like protein; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ctc:CTC00423 peptidase T. | Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase. | 0.458 |
| Cphy_3485 | Cphy_3486 | Cphy_3485 | Cphy_3486 | TIGRFAM: peptidase T-like protein; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ctc:CTC00423 peptidase T. | PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: cth:Cthe_3110 UBA/ThiF-type NAD/FAD binding fold. | 0.512 |
| Cphy_3485 | guaB | Cphy_3485 | Cphy_3287 | TIGRFAM: peptidase T-like protein; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ctc:CTC00423 peptidase T. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.434 |
| Cphy_3485 | rsmA | Cphy_3485 | Cphy_3899 | TIGRFAM: peptidase T-like protein; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ctc:CTC00423 peptidase T. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.637 |
| Cphy_3486 | Cphy_3485 | Cphy_3486 | Cphy_3485 | PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: cth:Cthe_3110 UBA/ThiF-type NAD/FAD binding fold. | TIGRFAM: peptidase T-like protein; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ctc:CTC00423 peptidase T. | 0.512 |
| guaB | Cphy_0312 | Cphy_3287 | Cphy_0312 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. | 0.868 |
| guaB | Cphy_2530 | Cphy_3287 | Cphy_2530 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase. | 0.828 |
| guaB | Cphy_3485 | Cphy_3287 | Cphy_3485 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | TIGRFAM: peptidase T-like protein; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ctc:CTC00423 peptidase T. | 0.434 |
| guaB | rsmA | Cphy_3287 | Cphy_3899 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.513 |
| rsmA | Cphy_3485 | Cphy_3899 | Cphy_3485 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | TIGRFAM: peptidase T-like protein; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ctc:CTC00423 peptidase T. | 0.637 |
| rsmA | guaB | Cphy_3899 | Cphy_3287 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.513 |