STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_3591PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: tte:TTE0448 methyl-accepting chemotaxis protein. (718 aa)    
Predicted Functional Partners:
Cphy_2843
PFAM: response regulator receiver; CheW domain protein; KEGG: amt:Amet_2732 putative CheW protein.
 
 
 0.911
Cphy_2690
CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; P2 response regulator binding domain protein; KEGG: cth:Cthe_0490 CheA signal transduction histidine kinases.
 
 
 0.907
Cphy_2689
PFAM: CheW domain protein; KEGG: cth:Cthe_0491 CheW protein.
 
 
 0.882
Cphy_0258
PFAM: CheW domain protein; KEGG: maq:Maqu_1966 putative CheW protein.
 
 
 0.881
Cphy_2448
PFAM: MCP methyltransferase CheR-type; KEGG: csc:Csac_0981 protein-glutamate O-methyltransferase.
 
 
 0.846
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.830
cheD
CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
   0.785
Cphy_2688
PFAM: CheC domain protein; KEGG: cth:Cthe_0492 CheC, inhibitor of MCP methylation.
 
 
 0.632
Cphy_2701
PFAM: response regulator receiver; KEGG: csc:Csac_1271 response regulator receiver protein.
 
  
 0.586
Cphy_2702
CheC, inhibitor of MCP methylation / FliN fusion protein; TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; KEGG: cth:Cthe_0478 CheC, inhibitor of MCP methylation.
 
 
 0.534
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.