STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_3909TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein; KEGG: swo:Swol_0047 transcription regulator AbrB. (85 aa)    
Predicted Functional Partners:
Cphy_2385
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.739
Cphy_0829
PFAM: GerA spore germination protein; KEGG: ctc:CTC01776 spore germination protein KA.
  
   
 0.732
Cphy_2497
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.706
Cphy_0210
TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: cth:Cthe_2618 stage III sporulation protein D, SpoIIID.
  
   
 0.688
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.676
Cphy_2498
KEGG: amt:Amet_2512 peptidase S55, sporulation stage IV, protein B; TIGRFAM: stage IV sporulation protein B; PFAM: peptidase S55 SpoIVB; SMART: PDZ/DHR/GLGF domain protein.
  
     0.663
Cphy_0480
TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; KEGG: amt:Amet_2220 stage V sporulation AD family protein.
  
     0.628
Cphy_3792
TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R; KEGG: cbh:CLC_0174 stage II sporulation protein R.
  
   
 0.622
Cphy_2469
RNA polymerase, sigma 28 subunit, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
    0.618
Cphy_0479
TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein; KEGG: drm:Dred_1106 SpoVA protein.
  
     0.603
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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