Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Cphy_3913TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: amt:Amet_0084 DNA polymerase III, delta prime subunit. (330 aa)    
Predicted Functional Partners:
Cphy_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.989
Cphy_1962
TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: cth:Cthe_1040 DNA polymerase III, delta subunit.
 
 
 0.987
Cphy_0335
KEGG: tte:TTE1818 DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein.
 
 0.986
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
  
0.933
Cphy_0145
KEGG: cth:Cthe_0996 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease.
   
 0.913
polC
DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.913
Cphy_3914
PFAM: protein of unknown function DUF327; KEGG: cth:Cthe_2106 protein of unknown function DUF327.
 
     0.840
Cphy_3483
PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: cth:Cthe_0559 single-strand binding protein/primosomal replication protein N.
  
 
 
 0.797
Cphy_3773
TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: cth:Cthe_2186 single-strand binding protein.
  
 
 
 0.783
Cphy_3911
Methyltransferase type 11; PFAM: methyltransferase small; Methyltransferase type 11; Methyltransferase type 12; KEGG: amt:Amet_0090 methyltransferase small.
 
     0.748
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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