STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_3937Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: cth:Cthe_1268 histidine kinase. (366 aa)    
Predicted Functional Partners:
Cphy_3936
PFAM: regulatory protein LuxR; response regulator receiver; KEGG: cth:Cthe_1267 two component transcriptional regulator, LuxR family.
 
 
 0.968
Cphy_3630
PFAM: regulatory protein LuxR; response regulator receiver; KEGG: cbe:Cbei_3785 two component transcriptional regulator, LuxR family.
 
 
 0.862
Cphy_0080
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; KEGG: bca:BCE_1863 DNA-binding response regulator, LuxR family.
 
 
 0.861
Cphy_0851
PFAM: regulatory protein LuxR; response regulator receiver; KEGG: ssa:SSA_0217 two-component system transcriptional regulator (CheY domain and HTH-like DNA-binding domain), putative.
 
 
 0.861
Cphy_1240
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: tde:TDE0149 DNA-binding response regulator.
 
 
 0.859
Cphy_0853
Putative signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: cac:CAC1454 membrane associated histidine kinase-like ATPase.
  
     0.770
Cphy_0079
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: bld:BLi04006 YxjM.
  
     0.747
Cphy_3938
PFAM: GCN5-related N-acetyltransferase; KEGG: tpt:Tpet_1016 GCN5-related N-acetyltransferase.
       0.527
Cphy_1604
Transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; KEGG: cps:CPS_1932 DNA-binding response regulator.
 
 
 0.477
Cphy_2448
PFAM: MCP methyltransferase CheR-type; KEGG: csc:Csac_0981 protein-glutamate O-methyltransferase.
      0.443
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.