STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TrpStryptophan--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)    
Predicted Functional Partners:
ANB40050.1
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.897
SerS
serine--tRNA ligase; Catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.814
ileS
isoleucine--tRNA ligase; IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme; Derived by automated computational analysis using gene prediction [...]
 
 
 0.775
PheT
phenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.747
ANB39705.1
Rhomboid family intramembrane serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.717
HisS
histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.714
LeuS
leucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.664
ANB38398.1
arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.664
MetG
methionine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.662
ValS
valine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.638
Your Current Organism:
Rhodovulum sulfidophilum
NCBI taxonomy Id: 35806
Other names: ATCC 35886, LMG 5201, LMG:5201, R. sulfidophilum, Rhodobacter sulfidiphilus, Rhodobacter sulfidophilus, Rhodopseudomonas sulfidophila, strain Hansen W4
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