STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOB36092.1Protein tyrosine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (163 aa)    
Predicted Functional Partners:
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
    
 0.680
AOB35666.1
Deoxyribodipyrimidine photolyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA photolyase family.
 
  
   0.640
AOB36390.1
Arsenic resistance protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.610
trxA_1
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.
  
 
 0.574
AOB35958.1
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.574
trxA_2
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.
  
 
 0.574
ybeY
rRNA maturation RNase YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
   0.500
iscR
Fe-S cluster assembly transcriptional regulator IscR; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.498
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.489
truA
tRNA pseudouridine(38,39,40) synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
   
   0.482
Your Current Organism:
Bordetella holmesii
NCBI taxonomy Id: 35814
Other names: ATCC 51541, B. holmesii, CCUG 34073, CDC F5101, CDC nonoxidizer group 2 (NO-2), CIP 104394, DSM 13416, LMG 15945, LMG:15945, NCTC 12912
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