node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KPH49728.1 | fabZ | HPU229336_06555 | HPU229336_07200 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3-hydroxyacyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.482 |
KPH49728.1 | lpxA | HPU229336_06555 | HPU229336_07195 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.986 |
KPH49728.1 | lpxC | HPU229336_06555 | HPU229336_00650 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.842 |
KPH49728.1 | lpxD | HPU229336_06555 | HPU229336_01000 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.985 |
KPH49728.1 | lpxK | HPU229336_06555 | HPU229336_07280 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.975 |
KPH50693.1 | KPH50694.1 | HPU229336_00640 | HPU229336_00645 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Selenocysteine lyase; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization. | 0.829 |
KPH50693.1 | KPH50696.1 | HPU229336_00640 | HPU229336_00655 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.825 |
KPH50693.1 | KPH50697.1 | HPU229336_00640 | HPU229336_00660 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cation transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | 0.819 |
KPH50693.1 | ftsH | HPU229336_00640 | HPU229336_00665 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.819 |
KPH50693.1 | lpxC | HPU229336_00640 | HPU229336_00650 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.829 |
KPH50694.1 | KPH50693.1 | HPU229336_00645 | HPU229336_00640 | Selenocysteine lyase; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.829 |
KPH50694.1 | KPH50696.1 | HPU229336_00645 | HPU229336_00655 | Selenocysteine lyase; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.830 |
KPH50694.1 | KPH50697.1 | HPU229336_00645 | HPU229336_00660 | Selenocysteine lyase; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization. | Cation transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | 0.824 |
KPH50694.1 | ftsH | HPU229336_00645 | HPU229336_00665 | Selenocysteine lyase; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization. | ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.824 |
KPH50694.1 | lpxC | HPU229336_00645 | HPU229336_00650 | Selenocysteine lyase; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.834 |
KPH50696.1 | KPH50693.1 | HPU229336_00655 | HPU229336_00640 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.825 |
KPH50696.1 | KPH50694.1 | HPU229336_00655 | HPU229336_00645 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Selenocysteine lyase; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization. | 0.830 |
KPH50696.1 | KPH50697.1 | HPU229336_00655 | HPU229336_00660 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cation transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | 0.832 |
KPH50696.1 | ftsH | HPU229336_00655 | HPU229336_00665 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.832 |
KPH50696.1 | lpxC | HPU229336_00655 | HPU229336_00650 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.829 |