STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPH50327.1Hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (770 aa)    
Predicted Functional Partners:
KPH51370.1
Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.986
KPH51142.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family.
 
  
 0.892
hypC
Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.877
KPH50005.1
Hydrogenase nickel incorporation protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.844
KPH50328.1
Thiamine monophosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.617
KPH51412.1
Hydrogenase 2 large subunit; Involved in hydrogen uptake; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 
 0.509
KPH50329.1
GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.496
hypA
Hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
   
 0.481
KPH50033.1
2-hydroxy-6-oxohepta-2,4-dienoate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.421
KPH51410.1
Protein hydD; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.421
Your Current Organism:
Helicobacter pullorum
NCBI taxonomy Id: 35818
Other names: ATCC 51801, CCUG 33837, CIP 104787, DSM 23160, H. pullorum, NCTC 12824
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