Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFU44037.1COG0477 Permeases of the major facilitator superfamily. (464 aa)    
Predicted Functional Partners:
AFU44038.1
Peptidase M48, Ste24p; COG0501 Zn-dependent protease with chaperone function.
       0.628
AFU48429.1
COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases.
 
   
 0.586
nagZ
Glycoside hydrolase family 3 domain-containing protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
 
   
 0.574
AFU44036.1
Two component transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
       0.525
AFU44035.1
COG0642 Signal transduction histidine kinase.
 
     0.501
AFU47660.1
N-acetyl-anhydromuranmyl-L-alanine amidase; COG3023 Negative regulator of beta-lactamase expression.
 
   
 0.492
AFU45600.1
Secretion protein HlyD family protein; COG0845 Membrane-fusion protein.
 
 0.472
anmK
anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
  
   
 0.434
AFU46039.1
COG1538 Outer membrane protein.
  
 0.419
Your Current Organism:
Acidovorax sp. KKS102
NCBI taxonomy Id: 358220
Other names: A. sp. KKS102
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